- Congdon & Carpenter Co.1
- Cook House1
- Cornet & Nightengale1
- Cousens & Tomlinson1
- Cowing & Co.1
- Craddock-Terry Company1
- Craffey and Crowell1
- Crandall & Morrison2
- Crane & Hurd3
- Crescent Candy Company1
- Crocker & Eldridge1
- Crocker & Ogden1
- Croft Brothers1
- Crystal Window Glass Works1
- Cumberland Mills1
- Cunningham, Frost & Throckmortons1
- Curry, Tunis & Norwood1
- Curtis & Curtis Co.1
- Curtis & Rickerson1
- Cushing, Olmsted and Snoss2
- Cutler & Neilson Paint & Color Co.1
- Cutler Paint & Glass Co.1
- D'Acheul Drug Company1
- D. Auerbach & Sons1
- D. Hodgman & Co.1
- D. Jayne & Son1
- D. N. & E. Walter Co.1
- D. P. Locher & Son, Bankers1
- D.J. Hennessy Mercantile Company1
- Dana Hardware Co.2
- Dana, Hyde & Co.2
- Daniel Scotten & Co.2
- Daniels & Fisher1
- Daniels, Cornell & Co.1
- Dater, Whaling & Co. State Mills1
- David S. Foster, Sons & Co.1
- David Trubee & Co.1
- Davis, Pitts & Co.1
- Day, Callaghan & Co.2
- DeGolyer Varnish Works1
- DeLong Brothers1
- Decatur & Hopkins Co.1
- Delamater Iron Works C. H. Delamatere & Co. Dr.1
- Deming Company1
- Denton & Wood1
- Detroit Lead Pipe & Sheet Lead Works1
- Devlin & Company2
- Dietz & Harper1
- Dodge Manufacturing Co.1
- Dodge, Davis & Co.1
- Downer & Bemis Brewing Co.1
- Downey Bros. Spoke & Bending Co.1
- Drummond Tobacco Co.1
- Dubuque Times1
- Dufur & Co.1
- Duncan & Goodell Co.1
- Dunham Manufacturing Company1
- Durand & Kasper Co.1
- E. A. Buck Co.1
- E. A. Cowee, Milller1