Oral history interview with Kenneth M. Brinkhous, 1991
Other Titles
Reminiscences of Kenneth M. Brinkhous : oral history, 1991; Oral history of Kenneth M. Brinkhous, 1991
Abstract
Childhood in rural Iowa; college and medical school at University of Iowa; early involvement in medical research in hemophilia; first researcher to discover deficiency in blood-clotting factor; involvement in Federation of American Societies for Experimental Biology; names of other early researchers and research journals; fatalism and lack of treatment in people with hemophilia prior to world War I I; post-war research into elements ("fractions") of blood plasma; discovery and purchase of dogs with hemophilia and consequent treatment attempts; development of first fresh frozen plasma bank; involvement with NHF; use of frequent transfusions to treat hemophilic dogs; development of first commercial concentrate and economic issues regarding delivery to patients; search for bodily source of Factor VIII; work on molecular genetics and hemophilia; advent of HIV; advantages versus disadvantages of pooling blood products; components of hemophilia "community"; benefits of having an "informed constituency"
Hemophilia--History.--United States; Hemophilia--Social aspects; Hemophilia--Political aspects; AIDS (Disease)--History.--United States; Animal experimentation; Physicians; Brinkhous, K. M. (Kenneth Merle), 1908-2000; Federation of American Societies for Experimental Biology